Abstract Background High-mobility group box 1 (HMGB1) is increased in breast cancer cells as the result of exposure to the secreted substances from cancer-associated fibroblasts and plays a crucial role in cancer progression and drug resistance.Its effect, however, on the expression of programmed death ligand 1 (PD-L1) in breast cancer cells has no
Through the example of Collections the cities of Reggio Calabria and Messina, which were completely destroyed by the earthquake of 28th December 1908, this paper examines the importance of anti-seismic regulations in the redefinition of the urban planning of these two cities, as well as the national situation during the early part of the century.It
A piezoelectric-driven microgripper with three-stage amplification was designed, which is able to perceive the tip displacement and gripping force.The key structure parameters of the microgripper were determined by finite element optimization and its theoretical Marble Ink amplification ratio was derived.The tracking experiments of the tip displace
The liquid shampoo is a Collections product that is generally used to clean hair and scalp.The additional active ingredient used in the liquid shampoo is neem leaves which contain polyphenols that have antibacterial effects.Neem leaves extract was made by hot infusion method with coconut oil as a solvent.The purposes of this research were to find t
An in-line holographic particle counter concept is presented and validated where multiple micrometer sized particles are detected in a three dimensional sampling volume, all at once.The proposed PIU is capable of detecting holograms of particles which sizes are in the lower μ m- range.The detection and counting Demi Tasse Spoons principle is b